Practice OCAT 9

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Across
  1. 2. Son of an Irish Earl, gave his name to an eponymous law linking pressures to volume changes. (5 letters)
  2. 3. A doubly Nobel technique maker. (6 letters)
  3. 4. Not referring to free water and snacks in the hotel minifridge, this term describes the way in which the nitrogenous bases in DNA pair up. (13 letters)
  4. 7. Jeeps have one on the back, more receptors than we need? (5 letters)
  5. 10. A product produced when the imidazole ring of a mast cell mediator is acted upon by a specific degrading enzyme (15 letters)
  6. 12. Off on a trip, forgot your drugs? Hope they are considerate towards your trespasses as you would towards others! (9 letters)
  7. 13. The protein product of the God gene. For real or just wishful thinking (acronym)? (4 letters)
  8. 17. Not a dominant male in a tribe, merely a subunit of a trimeric cytosolic protein involved in the effects of mediators that activate adenylate cyclase. (5 letters)
  9. 18. An endogenous mediator, whose effects on gastric acid secretion are potentiated by phosphodiesterase inhibitors (9 letters)
  10. 20. Interruptions so to speak. (7 letters)
  11. 21. Useful protein to have if you want to flee a raging bull—but not a bright idea to make judgements of this sort. (4 letters)
  12. 22. RNA pol II gets this job done. (13 letters)
  13. 24. A glandular mast cell maybe, though IgE will not find a sweet spot to latch onto. (3 letters)
  14. 25. A term that may cause some angst in political discussions, but physicists will simply ask them Watt's the big deal? (5 letters)
Down
  1. 1. It is touch and go for each one of us since so many of us are close by and all of us in our clan need to spread the word too. (16 letters)
  2. 5. Useful in and out of nuclei, pair bonding skills and their U-nique third member do CUT across multiple genomic processes. (11 letters)
  3. 6. THE one who spun. (8 letters)
  4. 8. This kind of enzyme not only limits the activity of a cAMP-dependent protein kinase but plays a crucial role in recycling desensitized receptors (11 letters)
  5. 9. Keep a pen with this in hand, especially when you stray into a garden of earthly delights in full bloom or drink reds of dubious vintage in fishy joints. (11 letters)
  6. 11. Basal levels of cAMP rapidly decrease when you add this agonist to isolated cells in culture, you suspect it could be one of this sort (7 letters)
  7. 14. Do I bite the hand that feeds me? Or really just the cell that has released me. I am that sort of mediator. (9 letters)
  8. 15. Your newly synthesised molecule changes the EC50 for acetylcholine from 80μM to 20μM but shifts the concentration response curve for noradrenaline to the right. You wonder if this sort of interaction is going on. (10 letters)
  9. 16. The agonist keeps calling, the receptor does not listen anymore—what has happened? (15 letters)
  10. 19. Not just an ice cap; property of molecules that struggle to cross cell membranes. (5 letters)
  11. 23. May have multiple partners, but this one dances to the left. (8 letters)