Puzzled by Pedigrees

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Across
  1. 2. Organization that publishes secondary findings guidelines
  2. 5. Type of inheritance where one altered copy is sufficient
  3. 7. Father of genetics who worked with pea plants
  4. 8. Genetic condition caused by trisomy 21
  5. 11. Inheritance pattern involving two altered copies
  6. 12. Classic metabolic condition managed with diet
Down
  1. 1. Last name of scientist whose X-ray diffraction work was critical to the DNA model
  2. 3. HELIX Structure of DNA described in 1953
  3. 4. Process of making RNA from DNA
  4. 6. Type of mutation that introduces a premature stop codon
  5. 9. Segment of DNA that codes for protein
  6. 10. Gene variant of uncertain significance (abbrev.)