Quorum Sensing

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Across
  1. 3. Vibrio fisheri and Hawaiian bobtail squid has symbiotic relationship by regulating
  2. 4. True or False. Las system negatively regulates rhlI and rhlR. Write the start of the letter
  3. 5. AIP acts on the transmembrane receptor___ which induces phosphorylation
  4. 6. Regulation of gene expression in response to fluctuation in cell population density
  5. 7. Effector of the Agr system that modulates virulence factor expression.
  6. 12. Motif present in LuxR and LasR DNA binding domain.
  7. 14. Vibrio fischeri: luciferase:: Pseudomonas aeruginosa:____
  8. 15. Where LuxR and LasR binds the AI
  9. 16. Phosphorylated AgrA undergoes a _____ change that allows it to preferentially bind and activate P2
  10. 17. Luciferase structural gene that is AI-responsive TS activator
  11. 19. activated after activation of P2 operon
  12. 20. Feedback loop regulated by Rhl QS system
  13. 23. Enzyme that hydrolyzes the ester bond of the ASL ring.
  14. 24. LuxR has it C terminus as it ___ binding domain
Down
  1. 1. AgrD is a peptide processed by _____ that results in thiolactone ring formation
  2. 2. Happens after mature AIP binds to AgrC
  3. 4. ________ inhibit QS by interfering with AHL signals which reduces virulence in P. aeruginosa infection in mice.
  4. 5. Encodes Agr B,D,C and A
  5. 8. AHL produced when rhlI gene activated
  6. 9. Regulatory effector if the Agr system
  7. 10. P.aeruginosa virulence factor regulated by the Rhl system
  8. 11. AI binding domain of luxR in Staphylococcus aureus
  9. 13. Produced by presence of exogenous AI, causes purple pigment
  10. 16. AgrD is a peptide processed at its end
  11. 18. Quorum sensing in gram negative bacteria have acyl homoserine lactones as signals which bind to ______ that activates/represses target genes
  12. 21. Luciferase plate test for a group II Stap aureus strain AIP using agrP3-luciferase with a type IV AIP would result in luciferase production.
  13. 22. The phosphate is transferred to AgrA, also known as___ regulator