Replication of DNA genome

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Across
  1. 4. __ protein that controls entry to the S phase of the cell cycle.
  2. 7. __ single stranded DNA virus that replicates in cells that are in S phase
  3. 9. - immediate early adenovirus protein that sequester Rb and activates promoters to produce pTp, Adpol and DBP viral proteins necessary for viral genome synthesis
  4. 10. - HSV-1 infection where no virus particles are produce and viral genome rest silence in the trigeminal ganglia
  5. 11. transcription activator of adenovirus genes necessary for viral DNA replication
  6. 12. - cell cycle phase of cell growth
  7. 13. - an autonomous replicating parvovirus that causes Erythema infectiosum in young children's
  8. 14. - cell cycle phase of preparation for cell division
  9. 15. - undergoes maintenance and productive replication in different cell layers of the skin
  10. 16. - Double stranded DNA virus where genome synthesis is primed by a viral protein
  11. 18. - enzyme that move directionally along a nucleic acid strands and opens strands of DNA
Down
  1. 1. __ Enzymes that remove dsDNA supercoils and separates interlocked daughter DNA molecules
  2. 2. - enzyme that provides an RNA primer to extend the 3' end of the chromosomes (telomeres)
  3. 3. - herpesvirus infection where viral particles are produced in the epithelial cells of the mouth
  4. 5. - can also be a helper virus to induce replication of adeno associated virus (AAV)
  5. 6. - a gamma herpesvirus that infects B cells
  6. 8. _ DNA strand were replication is discontinuous, with short Okazaki fragments as primers.
  7. 17. - origin of replication in herpesvirus genome that is activated in neural cells during reactivation of lytic viral replication