Review activity Concept Exam 2: Immunology

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Across
  1. 4. Enzyme responsible for junctional diversity within the V(D)J recombination process
  2. 5. T cells at the germinal center provide B lymphocytes with ______ signals
  3. 7. Antibodies mediate the _________ response
  4. 10. Bonds which hold together the heavy and light chain
  5. 13. B cells can act as antigen __________ cells for T lymphocytes
  6. 14. An Ig molecule is composed of two __________ heavy chains
  7. 15. The gene segments for undergoing class switch recombination are located on the ____ chain locus
  8. 17. Type of molecule present in professional antigen presentinc cells
  9. 18. Process by which antibodies bind to a pathogen so it can be phagocyted
  10. 20. Zone in the lymph node where B cells mostly accumulate
Down
  1. 1. Molecules which regulate the antibody class switch
  2. 2. After it has encountered its antigen, a B lymphocyte becomes
  3. 3. Process which generates higher affinity antibodies
  4. 6. Number of individual polypeptide chains in each antibody
  5. 8. Plasma cells initially secrete IgM, which is a ________ antibody
  6. 9. Loop within the variable region responsible for the highest degree of variation
  7. 11. Ig molecule capable of sensitizing B cells
  8. 12. Process by which antibodies inhibit the toxic effects or infectivity of pathogens or their products by binding to them
  9. 16. Enzyme responsible for class switch recombination
  10. 19. Number of complementarity determining regions in each antigen-bindig site of an antibody