Streptococcal & Childhood Viral Infection Testing

1. Serologic test that detects antibodies against streptolysin O to determine recent streptococcal infection.
3. Childhood virus that infects the respiratory tract and commonly affects infants and young children during winter
5. Oxygen-stable hemolysin responsible for beta hemolysis on blood agar plates
8. Bacterial enzyme that dissolves blood clots by converting plasminogen to plasmin.
10. Major virulence factor of Group A strep that prevents phagocytosis and is found on fimbriae.
11. Hair-like structures on bacteria that help Streptococcus pyogenes attach to human epithelial cells.
13. Enzyme produced by strep that breaks down hyaluronic acid in connective tissue and helps bacteria spread.
14. Virus transmitted by the fecal-oral route that commonly causes diarrhea and gastroenteritis in infants.

2. Test that detects antibodies to several streptococcal antigens using coated sheep red blood cells.
4. Antibody test useful for diagnosing post-streptococcal infections and often elevated in skin infections.
6. Paramyxovirus infection characterized by swelling of the parotid glands.
7. Oxygen-labile hemolysin produced by S. pyogenes that is antigenic and measured in serologic testing.
9. RNA virus in the Togaviridae family that causes German measles and can lead to congenital rubella syndrome if contracted during pregnancy.
12. RNA virus from the Paramyxoviridae family that causes measles and is associated with Koplik spots.