substance abuse

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Across
  1. 3. a drug that requires permission from a doctor to use
  2. 4. a drug that can be obtained only by means of a physician's prescription
  3. 6. a poisonous alkaloid C10H14N2 that is the chief active principle of tobacco and is used as an insecticide
  4. 8. to inhale vapor through the mouth from a usually battery-operated electronic device
  5. 10. the act of refusing or denying
Down
  1. 1. a strong and harmful need to regularly have something (such as a drug) or do something
  2. 2. a battery-operated device that is typically designed to resemble a traditional cigarette
  3. 5. a tall widely cultivated Asian herb
  4. 7. a nonintoxicating cannabinoid found in cannabis and hemp
  5. 9. Food and Drug Administration