Test on Diabetes mellitus

12345678910111213141516171819
Across
  1. 1. The most rapidly acting insulin analogue
  2. 4. This organ receives the highest concentration of endogenous insulin but not the exogenous insulin
  3. 7. Only oral ADA that has been demonstrated to reduce macrovascular events in type 2 DM
  4. 9. This injectable ADA used in type 2 DM and recently approved for management of obesity
  5. 10. Long term use of metformin can result in this adverse effect
  6. 13. A hormone, which is a “universal inhibitor”, inhibits the release of insulin from beta cells
  7. 14. This insulin can be given intravenously
  8. 16. The longest acting insulin, which can be mixed with other insulins too
  9. 17. Long acting inhaled insulin preparation (approved by US FDA in 2014, withdrawn from market, by EMA in 2018)
  10. 18. Insulin secretion will_______by cholinergic-muscarinic activation by Ach
  11. 19. Secreted by beta cells of pancreas along with insulin that also helps in decreasing blood sugar
Down
  1. 2. Beta blockers can mask all the warning signs of hypoglycaemia, except this one
  2. 3. The only drug approved for treatment of both type 1 DM as well as type 2 DM (other than insulin)
  3. 5. Insulin acts on this specific receptor located on cell membrane of every cells (practically)
  4. 6. This ADR of insulin occurs due to local reaction on subcutaneous fat around injection site
  5. 8. The most potent insulinotropic sulfonyl urea, which has property of sequestered in beta cells
  6. 11. This DPP4 inhibitor does not requires dose adjustment in renal failure patients, but it increases risk of heart failure
  7. 12. All insulin or insulin analogues preparations available at neutral pH, except this one, which is at pH 4
  8. 13. Accumulation of this substance in tissue is responsible for long term complications in diabetes (like end organ damage)
  9. 15. A long acting insulin, should never mix with other insulin