The discovery of RNA catalysis

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Across
  1. 2. a type of catalyst that iš produced by living organisms
  2. 3. a substance that increases the rate of a chemical reaction without itself undergoing any permanent chemical change.
  3. 4. a molecule where a strand of RNA and a strand of DNA are annealed together, often forming an intermediate structure during processes like transcription
  4. 5. period in evolution where RNA stored genetic information and acted as an enzyme
  5. 7. an essential enzyme that processes the 5' ends of precursor transfer RNAs (pre-tRNAs)
  6. 9. the ability of a substance to accelerate a chemical reaction by providing an alternative pathway with lower activation energy
  7. 10. triphosphate a vital nucleotide in biology that acts as an energy source and a signaling molecule
  8. 11. an intercellular structure made of both RNA and protein, and it is the site of protein synthesis in the cell
  9. 14. an American chemist who shared the 1989 Nobel Prize in Chemistry with Sidney Altman for their discovery of the catalytic properties of RNA.
  10. 15. crucial enzyme that synthesizes DNA molecules, essential for DNA replication and repair in all living organisms
Down
  1. 1. the ciliated protozoan which Thomas Cech was studying transcription of ribosomal RNA genes
  2. 6. transitional evolution phase where RNA and proteins began working together.
  3. 8. an RNA motif that catalyzes reversible cleavage and ligation reactions at a specific site within an RNA molecule
  4. 12. RNA molecules that function as biological catalysts, similar to protein enzymes
  5. 13. any nucleotide sequence within a gene that is not expressed or operative in the final RNA product.