The ID Quest

123456789101112131415161718192021222324252627282930313233
Across
  1. 3. Emerging multidrug-resistant yeast causing healthcare-associated outbreaks
  2. 6. Initial test guiding early empiric antimicrobial therapy
  3. 7. Preventive antimicrobial strategy in high-risk patients
  4. 8. Diagnostic gold standard for confirming osteomyelitis before prolonged therapy
  5. 10. Adjustment of antibiotics based on culture results rather than clinical improvement alone
  6. 11. Disposition strategy for a stable patient requiring prolonged intravenous therapy after hospital discharge
  7. 12. Most important intervention in a patient with abscess who is not improving on appropriate antibiotics
  8. 13. Organism associated with hypermucoviscous liver abscess in certain populations
  9. 15. Encapsulated yeast causing meningitis in immunocompromised hosts
  10. 20. Positive culture without clinical signs of infection that should not prompt treatment
  11. 21. Laboratory data used to determine the most appropriate targeted antibiotic
  12. 22. Alternative to vancomycin for MRSA bacteremia that cannot be used in pneumonia
  13. 24. Rapid diagnostic modality used when cultures are negative but suspicion remains high
  14. 26. Escalation agent for severe infections caused by ESBL-producing organisms
  15. 29. Broad empiric therapy often de-escalated once culture data are available
  16. 30. Organism frequently resistant to vancomycin in hospitalized patients
  17. 32. Resistance mechanism suspected when ceftriaxone fails in a gram-negative bacteremia
  18. 33. Biomarker sometimes used to support early discontinuation of antibiotics
Down
  1. 1. Oral option for MRSA with excellent bioavailability but risk of thrombocytopenia
  2. 2. New infection that develops during treatment of an existing one
  3. 4. Patient with bacteremia and persistent fevers despite antibiotics requires evaluation for this organism’s metastatic complications
  4. 5. Pathogen to consider in hospital-acquired infections with intrinsic resistance patterns
  5. 9. First-line therapy for MRSA bacteremia requiring drug level monitoring to avoid nephrotoxicity
  6. 14. Marker used to assess severity and prognosis in sepsis
  7. 15. Preferred therapy for MSSA bacteremia despite availability of broader-spectrum agents
  8. 16. Preferred imaging when transthoracic study is negative but suspicion for valvular infection remains high
  9. 17. Blood culture result often due to skin flora in a single bottle without clinical correlation
  10. 18. Hospital-specific data used to guide empiric antibiotic selection
  11. 19. Diagnosis that must be excluded in all patients with Staphylococcus aureus bacteremia using repeat cultures and imaging
  12. 23. Mold causing angioinvasive disease in neutropenic patients
  13. 25. Test that must be repeated to document clearance in bacteremia
  14. 27. Mechanism explaining persistent infection on prosthetic material despite appropriate antibiotics
  15. 28. Enzyme that renders carbapenems ineffective in multidrug-resistant organisms
  16. 31. Syndrome defined by infection plus organ dysfunction