The Wonders of Nonspecific Immunity

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Across
  1. 4. the largest of all leukocytes, which differentiate either into macrophages or dendritic cells
  2. 5. this mediator is released when cytokines bind to mast cells; causes allergic reactions
  3. 7. this process makes it easier for phagocytic cells to recognize and engulf pathogens; involves coating the pathogen in a chemical substance
  4. 8. pyrogens affect this part of the body, causing body temperature to rise, and fever to occur as a result
Down
  1. 1. these white blood cells are able to move through the walls of blood vessels to the site of a bacterial infection; are the most common type of white blood cell
  2. 2. also known as swelling, is one of the five signs of an inflammatory response
  3. 3. these proteins are important for cell to cell communication
  4. 6. this type of immunity has no memory component
  5. 9. pattern recognition receptors and toll-like receptors are designed to bind to these structures, which include peptidoglycan and flagellin
  6. 10. formed when the complement proteins C6, C7, C8, and C9 assemble; leads to pores being formed within the membranes of gram-negative bacteria