Transdermal Drug Delivery

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Across
  1. 1. the application of low-frequency ultrasound acoustic waves to transport drugs through the skin
  2. 4. generation: what is caused from the conversion of ultrasound energy to heat energy on the surface of the skin and some deeper tissues
  3. 5. An Electrochemical method that enhances the transport of some solute molecules by creating a potential gradient through the skin with an applied electrical current or voltage
  4. 7. which transdermal spray gel containing desoximetasone treats inflammation and itching caused by plaque psoriasis
  5. 9. example of a transdermal nanoemulsion containing diclofenac developed for relieving pain
  6. 10. what type of patch has the drug matrix layer directly incorporated into the backing layer
  7. 11. a contraceptive transdermal patch
  8. 12. this transdermal dosage form is designed to support the passage of drug substances from the surface of the skin through it various layers into the systemic circulation
  9. 15. nanoparticles provide a ____ and controlled release behavior
  10. 16. area of the body with great skin penetration
  11. 19. Unidirectional flow of fluid along cell membranes in response to bubbles caused by cavitation
  12. 20. which drug is most often administered from 1-10% in a sonophoresis gel
  13. 22. which transdermal spray gel containing clobetasol propionate treats eczema and psoriasis
  14. 25. examples of this transdermal method are azone, ethanol, terpenes, oleic acid, and Transcutol
  15. 29. ___ penetration occurs on the trunk, forearms, palms, and soles
  16. 31. gel: which transdermal dosage form is an aqueous solution in the form of coarse droplets \
  17. 32. what mechanical system consists of nanoparticles ranging form 50 to 500 nm
  18. 33. what type of drug penetration allows drugs to travel down the follicles or the sweat glands
  19. 36. what part of the patch stores the drug in a liquid or gel form
  20. 37. what part of the of the patch provides the ability to adhere the patch to the skin with minimal pressure
  21. 39. Which microneedles provide a direct path for drug delivery into the dermis
  22. 40. Nanoparticles are classified into several types according to their _____
  23. 41. component of the stratum corneum is considered an important determinant in the first step of absorption
  24. 42. what drug has been used to induce sweating in the diagnosis of cystic fibrous using iontophoresis
  25. 45. what type of drug penetration allows drugs to permeate through the imperfections in the cells
  26. 46. transdermal spray gels can drive small ____ drugs into the stratum corneum
  27. 47. which transdermal spray gel containing terbinafine HCl treats athletes foot /ringworm and is an OTC
Down
  1. 1. Which microneedles are used for skin pretreatment to increase skin permeability
  2. 2. Which transdermal spray gel containing betamethasone treats inflammation and itching caused by plaque psoriasis
  3. 3. What is the rate-limiting barrier to transdermal drug transport (primary challenge)
  4. 6. what part of the patch is commonly made of polyethylene with tons of micropores
  5. 8. what part of the patch protects the system form the environment
  6. 13. what type of patch is designed to contain the drugs in a reservoir
  7. 14. what transdermal patch can be used to help an individual to quit smoking
  8. 17. what drug has been used with iontophoresis as an anti-inflammatory to joints
  9. 18. a disadvantage of iontophoresis is potential skin irritation at ____ current densities
  10. 21. which transdermal patch can be used to treat chronic pain
  11. 23. micro and nanoemulsion contain a high concentration of ___ (15-25%)
  12. 24. examples of this transdermal method are ionophoresis, sonophoresis, and microneedles
  13. 26. nanoparticles have a ____ contact with the skin enhancing its permeation through the stratum corneum
  14. 27. Which microneedles swell upon insertion, creating a pathway for drug diffusion
  15. 28. which transdermal patch treats high blood pressure
  16. 30. the formation and collapse of tiny air bubbles in a liquid that comes in contact with the ultrasound waves
  17. 34. Which microneedles are biodegradable materials that encapsulate the drugs and dissolve in the skin
  18. 35. what is entrapped inside a lipid matrix in a nanoparticle
  19. 36. Examples of this transdermal method are transdermal patches, spray gels, and nanocarriers
  20. 38. what drug has been used with iontophoresis as a topical anesthetic
  21. 43. what type of drug penetration allows solutions to diffuse through the intercellular lipid
  22. 44. what type of adhesive cover the entire patch and is most commonly used