TTS Metabolisme Xenobiotik Kelompok 17

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Across
  1. 6. Long-term scarring in tissues that can follow repeated chemical injury.
  2. 8. A defined body “space” used in models to track where a chemical moves and accumulates.
  3. 9. An enzyme that untangles DNA during copying; interference can lead to genetic damage.
  4. 10. A liver immune cell that senses damage signals and can amplify inflammation.
  5. 11. Related to making steroid hormones, which some chemicals can disrupt.
  6. 12. A computer method that predicts how a chemical might fit and bind to a protein.
  7. 14. When a flat chemical slips between DNA bases and can disturb normal DNA function.
Down
  1. 1. Proteins that package DNA and help control which genes are turned on or off.
  2. 2. Continuous monitoring to detect harmful effects and safety signals over time.
  3. 3. When different receptor or signaling pathways influence each other instead of acting alone.
  4. 4. A very reactive positively charged carbon that can damage DNA or proteins.
  5. 5. Using computer methods to organize and predict chemical behavior and toxicity.
  6. 7. A lab test system that produces a measurable signal when a receptor or gene pathway is activated.
  7. 13. A ring-shaped chemical structure that can form reactive metabolites during breakdown.