Acyclovir

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Across
  1. 1. Enzyme that activates Acyclovir in infected cells
  2. 4. Antiviral drug that mimics guanosine
  3. 7. HSV TK has greater ___ ___ for Acyclovir than VZV TK
  4. 11. Describes Acyclovir’s low toxicity due to targeting infected cells
  5. 13. __ ___ is the process by which viral DNA replication is halted
Down
  1. 2. Pathway viruses use to replicate DNA. Hint: not de novo
  2. 3. Viral DNA ___ is the enzyme inhibited by Acyclo-GTP
  3. 5. Acyclovir is not a nucleotide analogue, it is a ___ analogue
  4. 6. Virus also affected by Acyclovir but with lower sensitivity
  5. 8. Key structural feature of Acyclovir regarding its sugar group
  6. 9. Acyclo-GTP has the highest ___ for viral DNA polymerase
  7. 10. Type of nitrogenous base Acyclovir resembles
  8. 12. Ayclo-___ is the most potent form of Acyclovir
  9. 14. Virus most sensitive to Acyclovir