We are looking for the name of a terrible doctor who carried out experiments on animals in 6 letters

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Across
  1. 3. cross the genes two different species
  2. 5. give permission
  3. 7. an experiment can get 'out of ...' like the monster of Dr Frankenstein
  4. 9. acting with no consideration of the consequences!
  5. 11. a live organism native and restricted to a certain place
  6. 12. a synonym for dangerous
Down
  1. 1. l'inverse de moral et d'éthique
  2. 2. discutable, qui ne fait pas l'unanimité
  3. 4. engagé
  4. 6. a genetic manipulation that consists in replacing a gene with molecular scissors
  5. 7. a genetic manipulation with an identical species
  6. 8. another verb for prohibit or ban
  7. 10. 'play Dr Frankenstein': jouer les apprentis sorciers