B Cells

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Across
  1. 1. This antibody is used in allergic reactions
  2. 2. T cells can only recognize this protein in T cell dependent activations
  3. 6. Plasma B cells are ___-____
  4. 7. Antigen that B cell binds to (2 words w/o spaces)
  5. 10. This antibody subclass is used to opsonize invaders for macrophages and neutrophils
  6. 12. This antibody cannot be used for complement fixing
  7. 13. This region of the antibody changes during class switching
  8. 15. A second protein receptor that can bind to complement fragments on an invader
  9. 17. How many chromosome 14s does a B cell have?
  10. 18. These are the chemicals that include histamine
  11. 19. This cell is an antibody factory (3 words w/o spaces)
  12. 22. This granule causes capillary permeability to increase, therefore increases fluid release such as a runny nose
  13. 24. Where B cells are born (2 words w/o spaces)
  14. 25. This is where T cell independent activation is found
Down
  1. 1. This antibody is most usually used when B cells initially produce antibodies
  2. 3. Lots of B cell receptors clustered together that bind to multiple receptors on the antigen
  3. 4. The antigen that binds to molecules on B cells surface, not to B cell receptors
  4. 5. This is when B cells are able to change their class of antibody produced (2 words w/o spaces)
  5. 7. What protein is on a B cell and used for co-stimulation as well as binds to CD40L on helper T cells
  6. 8. This antibody can fix the complement system like IgM but it requires two of them to do it
  7. 9. Region on the antigen that the B cell receptor binds to
  8. 11. This means that the cell has a higher chance to bind to the antigen (2 words w/o spaces)
  9. 14. This causes genes in the B cell receptor to change (2 words w/o spaces)
  10. 16. This antigen causes allergic reactions
  11. 20. This cell can defend against future invaders in the body and are long-lived (3 words w/o spaces)
  12. 21. Somatic hypermutation gene segments have a high level of _____
  13. 23. This are of the antibody is cut off and replaced in class switching