Across
- 1. This antibody is used in allergic reactions
- 2. T cells can only recognize this protein in T cell dependent activations
- 6. Plasma B cells are ___-____
- 7. Antigen that B cell binds to (2 words w/o spaces)
- 10. This antibody subclass is used to opsonize invaders for macrophages and neutrophils
- 12. This antibody cannot be used for complement fixing
- 13. This region of the antibody changes during class switching
- 15. A second protein receptor that can bind to complement fragments on an invader
- 17. How many chromosome 14s does a B cell have?
- 18. These are the chemicals that include histamine
- 19. This cell is an antibody factory (3 words w/o spaces)
- 22. This granule causes capillary permeability to increase, therefore increases fluid release such as a runny nose
- 24. Where B cells are born (2 words w/o spaces)
- 25. This is where T cell independent activation is found
Down
- 1. This antibody is most usually used when B cells initially produce antibodies
- 3. Lots of B cell receptors clustered together that bind to multiple receptors on the antigen
- 4. The antigen that binds to molecules on B cells surface, not to B cell receptors
- 5. This is when B cells are able to change their class of antibody produced (2 words w/o spaces)
- 7. What protein is on a B cell and used for co-stimulation as well as binds to CD40L on helper T cells
- 8. This antibody can fix the complement system like IgM but it requires two of them to do it
- 9. Region on the antigen that the B cell receptor binds to
- 11. This means that the cell has a higher chance to bind to the antigen (2 words w/o spaces)
- 14. This causes genes in the B cell receptor to change (2 words w/o spaces)
- 16. This antigen causes allergic reactions
- 20. This cell can defend against future invaders in the body and are long-lived (3 words w/o spaces)
- 21. Somatic hypermutation gene segments have a high level of _____
- 23. This are of the antibody is cut off and replaced in class switching
