Across
- 1. third protein that binds to the α and β chains of class II MHC molecules
- 4. MHC molecules having many forms
- 6. the most important type of cells during the initial stages of attack
- 9. region where T cells temporarily stay that surrounds the central arteriole
- 10. the cytokine receptor that T cells express to migrate to the thymic medulla
- 12. There is a second cell type which has been implicated in testing for tolerance of self antigens in the thymus
- 13. consequence if a T cell fails the MHC restriction test
- 14. proteins that replace defective proteins in the proteasome of macrophages
Down
- 2. the transcription factor drives the expression of tissue-specific antigens in medullary thymic epithelial cells
- 3. cells found in lymphoid follicles and are critical for B cell activation
- 4. patches of smooth cells that are embeded among cells that line the small intestine
- 5. are blood vessels found in the lymph nodes that lymphocytes travel through
- 7. type of CD4+ T cell helps dampen the immune response
- 8. molecules that display protein fragments to T cells
- 11. molecule competes with CD28 for binding to B7 on APCs
- 12. organ responsible for T cell tolerance induction
