Immunity

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Across
  1. 5. Our skin is part of the ____ line of defense in immunity
  2. 6. Lymphocytes and Monocytes are ____
  3. 12. Portions of cells, viruses, and molecules the body recognizes as foreign
  4. 14. The primary function of B cells is to secrete ___
  5. 15. The three-dimensional shape of the antigen region that is recognized by the immune system
  6. 19. Normal microbiota changing pH to favor their own growth is an example of microbial ____
  7. 20. Clumping of antigen-bound antibodies which slows activity of pathogens and increases chance of phagocytosis
  8. 21. Signal leukocytes to move to a site of inflammation or infection
  9. 24. The ____ cascade utilizes proteins, triggers multiple pathways, and results in the lysis of foreign cells
  10. 25. Proteins released by host cells to nonspecifically inhibit the spread of viral infections
  11. 28. In phagocytosis, ___ surround the microbe to help internalize it
  12. 30. An enzyme found in saliva, tears, sweat, etc. that breaks down bacterial cell walls
  13. 32. The role of histamine in the inflammation process is to cause ___
  14. 33. Prostaglandins and leukotrienes increase the ____ of vessels
  15. 34. Chemicals such as lysozyme and toll-like receptors are part of ____ defenses
  16. 35. ____ immune response is often directed against extracellular pathogens and toxins
  17. 37. Inflammation is a ____, nonspecific response to tissue damage
  18. 38. ____ cells are phagocytic cells in the skin and mucous membranes
Down
  1. 1. ____ acquired active immunity come from vaccines
  2. 2. The _____ system is made up of vessels, cells, tissues, and organs that are directly involved in adaptive immunity
  3. 3. The type of cytokines that act as a signal among leukocytes
  4. 4. The third line of defense if part of ____ immunity
  5. 7. The inflammation process allows ___ proteins to seep into damaged tissue
  6. 8. The antibody function that stimulates phagocytosis
  7. 9. Structures present on microbes that are not found on human cells, recognized by toll-like receptors
  8. 10. ____ membranes are part of first line of defense
  9. 11. The first line of defense in immunity utilizes _____ barriers
  10. 13. The term for all white blood cells
  11. 16. B lymphocytes mature in the red bone marrow while T lymphocytes mature in the ___
  12. 17. Naturally acquired ____ immunity occurs in a fetus or newborn from antibodies being passed through the placenta or in breast milk
  13. 18. The second line of defense is part of ____ immunity
  14. 22. In _____ immune response, T cells act against intracellular pathogens
  15. 23. A small percentage of B cells become ____ B cells which are long-lived and complementary to the specific antigen that triggered their production
  16. 26. Fevers enhance _____ effect and inhibit some microbial growth
  17. 27. Immune cells that treat ___ as foreign are normally eliminated during immune system development
  18. 29. Basophils, Eosinophils, and Neutrophils are all ____
  19. 31. A _____ white blood count can help show signs of disease
  20. 33. Iron-binding proteins in ____ can sequester iron to prevent invading pathogens from using it
  21. 36. A fever is caused by _____ triggering the hypothalamus to reset at a higher temperature