Innate Immune System

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Across
  1. 2. A substance that causes fever as part of an immune response
  2. 3. Organelle that breaks down engulfed pathogens in phagocytes
  3. 8. Immune cell that releases histamine during inflammation
  4. 9. A large phagocytic cell that plays a role in innate immunity
  5. 10. Chemical released by mast cells during inflammation
  6. 14. An example of a parasite that can trigger innate responses
  7. 16. A type of white blood cell that engulfs and digests pathogens
  8. 18. The swelling, heat, and redness caused by immune activity
  9. 21. Fluid secreted by skin that contains antimicrobial properties
  10. 24. A protein that can break down microbial components
  11. 25. Movement of immune cells toward chemical signals
  12. 26. A type of white blood cell containing granules for defense
  13. 28. Widening of blood vessels during inflammation
  14. 30. A physical or chemical defence that prevents pathogen entry
  15. 32. Beneficial microbes that help defend against harmful pathogens
  16. 34. A disease-causing microorganism
  17. 36. A condition where the immune system attacks the body’s own cells
  18. 37. A substance that enhances phagocytosis by marking pathogens
  19. 38. A white blood cell involved in allergic and inflammatory responses
Down
  1. 1. A chemical that interferes with viral replication
  2. 4. A group of proteins that helps destroy pathogens
  3. 5. Molecules shared by many microbes that innate cells detect
  4. 6. Non-animal organism that also displays innate immune responses
  5. 7. An increase in body temperature in response to infection
  6. 11. A sticky secretion that traps pathogens at body surfaces
  7. 12. Swelling caused by fluid leakage during inflammation
  8. 13. Another word for non-specific or innate immune response
  9. 15. The body’s largest organ and a key physical barrier
  10. 16. A protein released by NK cells that creates holes in target cells
  11. 17. A structure on immune cells that detects signals or pathogens
  12. 19. A molecule that can trigger an immune response
  13. 20. A type of killer cell that destroys virus-infected cells
  14. 22. Protein on immune cells that detects common pathogen features
  15. 23. Any molecule or cell that the immune system recognises as foreign
  16. 27. The specific part of an antigen recognized by immune cells
  17. 29. A fast-responding phagocytic white blood cell
  18. 31. Signalling protein released by immune cells to communicate
  19. 33. The pH condition of the stomach that kills ingested microbes
  20. 35. White blood cell that fights multicellular parasites