Across
- 5. A molecule (often a protein) to which a drug binds to produce its effect.
- 7. The type of drug metabolism that involves conjugation reactions, such as glucuronidation.
- 8. The collective term for the interactions (e.g., ionic, van der Waals) that bind a drug to its target.
- 12. A drug that binds to a receptor and activates it, mimicking the natural messenger.
- 13. The process by which a drug is transported via the bloodstream to various tissues of the body.
Down
- 1. A type of enzyme inhibition where the inhibitor binds covalently and permanently to the active site.
- 2. The initial process by which a drug enters the bloodstream from its site of administration.
- 3. A type of bond, crucial for drug-receptor interactions, that involves an electron-deficient hydrogen and an electron-rich heteroatom.
- 4. An inactive compound that is converted into an active drug within the body.
- 6. The study of what the body does to the drug (ADME).
- 9. A strategy in drug design involving the replacement of a group in a molecule with another that has similar physicochemical properties.
- 10. A property describing a drug's "fat-loving" nature, crucial for crossing cell membranes.
- 11. The type of drug metabolism that involves reactions like oxidation and reduction.
