Medicinal chemistry

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Across
  1. 5. A molecule (often a protein) to which a drug binds to produce its effect.
  2. 7. The type of drug metabolism that involves conjugation reactions, such as glucuronidation.
  3. 8. The collective term for the interactions (e.g., ionic, van der Waals) that bind a drug to its target.
  4. 12. A drug that binds to a receptor and activates it, mimicking the natural messenger.
  5. 13. The process by which a drug is transported via the bloodstream to various tissues of the body.
Down
  1. 1. A type of enzyme inhibition where the inhibitor binds covalently and permanently to the active site.
  2. 2. The initial process by which a drug enters the bloodstream from its site of administration.
  3. 3. A type of bond, crucial for drug-receptor interactions, that involves an electron-deficient hydrogen and an electron-rich heteroatom.
  4. 4. An inactive compound that is converted into an active drug within the body.
  5. 6. The study of what the body does to the drug (ADME).
  6. 9. A strategy in drug design involving the replacement of a group in a molecule with another that has similar physicochemical properties.
  7. 10. A property describing a drug's "fat-loving" nature, crucial for crossing cell membranes.
  8. 11. The type of drug metabolism that involves reactions like oxidation and reduction.