Xmas Meal 2025

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Across
  1. 1. A class of G proteins that cause the release of intracellular calcium. Also slang for "good looking guy".
  2. 3. Cold word that sounds like I see !
  3. 4. A neurodegenerative disease associated with old age that is often treated with cholinesterase inhibitors
  4. 5. Make one of these if you find a coin in your Christmas pudding
  5. 6. A folic acid antagonist used to treat both arthritis and cancer, and causes myelosuppression
  6. 12. Our favourite TC media named after a famous Italian-American virologist
  7. 13. A European doctor named Paracelsus declared that at high doses, all drugs become this....
  8. 15. What you want if you’re dreaming of a white Christmas
  9. 16. A highly effective antipsychotic requiring frequent blood tests due to a life-threatening side effect
  10. 17. Noisy gift received on the eleventh day of Christmas?
Down
  1. 1. It might arrive at your Christmas dinner by boat
  2. 2. The biophysical term that defines the strength of binding of a drug to its molecular target
  3. 3. A type of agonist that produces the opposite effect of a full agonist.
  4. 5. It’s often mulled over at Christmas!
  5. 6. 1947 and 1994 Christmas film: _______ on 34th Street
  6. 7. A SERM used in the treatment of patients who are at high risk for, or have been diagnosed with, ER positive breast cancer.
  7. 8. The name given to cholinergic receptors that are ligand-gated ion channels
  8. 9. Eye protection you’re unlikely to need in December
  9. 10. The abbreviation that reflects the concentration at which 50% of receptors are occupied by drug
  10. 11. The traditional way to cook a turkey at Christmas
  11. 14. Seasonal phrase: Glad tidings of comfort and ___