Hematology Crossword

Edit Answers
123456789101112131415161718192021222324252627282930313233343536373839404142434445464748495051525354555657585960616263646566676869707172737475767778
Across
  1. 1. Age group most commonly affected in drug-induced immune thrombocytopenia.
  2. 5. Serum thrombopoietin levels in TAR are considered as?
  3. 7. A disorder related to preeclampsia/eclampsia and is seen in the peripartum period and defined by the presence of microangiopathic HA, elevated liver enzymes, and low platelet count.
  4. 8. It is the most consistent feature of WAS-associated disease.
  5. 12. Thrombocytopenia, MAHA, fever, neurologic abnormalities, renal and organ dysfunction are the symptoms typically seen in Thrombotic thrombocytopenic purpura (TTP) and are collectively known as?
  6. 14. This is the hallmark of Purpura fulminans that is characterized by "blackening" of the extremities.
  7. 18. Organ that is deficient in CAMT that leads to thrombocytopenia.
  8. 19. It is a kind of venous thrombosis that may occur during infection, malignancy, or infusion of intravenous drug.
  9. 20. It refers to the occurrence of acute neurologic abnormalities in a preeclamptic woman during peripartum period.
  10. 24. It is a spider web-like lesions that appears as pink or red, twisted or tortuous (disorganized).
  11. 25. A characteristic staining presented by Waldenstrom's Purpura that gives a yellowish-brown color that resembles cayenne pepper.
  12. 27. It is one of the most frequent causes of drug-induced thrombocytopenia, where it act as a hapten.
  13. 28. Disseminated Intravascular Coagulation is characterized in this condition because it typically arises from primary complications.
  14. 29. Included in the pregnancy-associated thrombocytopenia that is characterized by hypertension and proteinuria. It is considered as a major contributor to maternal and fetal morbidity and mortality.
  15. 31. Clinical manifestation of red blood cell extravasation into mucosa or skin.
  16. 33. Patients with Hermansky-Pudlak Syndrome and Chediak-Higashi Syndrome both shows what specific skin discoloration?
  17. 36. A type of TTP in which the thrombi is found most extensively in the heart, pancreas, spleen, kidney, adrenal gland and brain and are composed mainly of platelets and vWF.
  18. 38. A self-limiting, spontaneous remissions type of ITP, which usually does not require treatment. It is most commonly seen in children.
  19. 45. A type of purpura commonly seen in individuals with emotional problems or stress.
  20. 46. It is the more severe type of CAMT where it is usually characterized by constantly low platelet count and early onset of pancytopenia.
  21. 50. This terms means that the exact cause of the condition is unknown, though it is known to involve the immune system, thus autoantibody is mainly involved in this condition.
  22. 51. GPIIb/IIIa complex deficiency in Glanzmann's Thrombasthenia is associated in what mechanism of platelet function?
  23. 54. HIV-related thrombocytopenia primarily evaluates what specific kind of infection?
  24. 56. In this type of acquired vascular disorder, leading is caused by deposition of amyloid protein around small blood vessels, resulting in vessel fragility
  25. 57. One characteristic laboratory finding in the peripheral blood smear of patients with TTP, together with basophilic stippling, nucleated cells, and schistocytes.
  26. 61. In DIC, platelets and coagulation factors undergoes this mechanism, which leads to prolonged PT and aPTT test results.
  27. 62. A gene that is mutated in Marfan Syndrome that results in abnormalities in connective tissues and risk for bleeding and bruising.
  28. 64. What pathway in the coagulation cascade is prolonged if Factor VII is deficient?
  29. 66. von Willebrand disease have no response to this aggregating agent.
  30. 69. A condition associated in platelet distribution where the spleen is enlarged, therefore, trapping the platelets that usual, thus, reducing the number of available platelets in the bloodstream.
  31. 70. Treatment method for immunoglobulin transfusion in chronic ITP.
  32. 71. A clinical manifestation in deep tissue bleeding characterized by excessive bleeding in the joints.
  33. 73. A deficiency disorder that is characterized in mutation resulting in the substitution of arginine with glutamine at number 506 of Factor V.
  34. 74. Characteristic of RBCS in blood smear of patients with hereditary TTP.
  35. 76. What is the shape of the platelets usually seen in Bernard-Soulier Syndrome.
  36. 77. Hereditary TTP is a rare disorder that affects neonates that were born with this specific type of stain.
  37. 78. The usual characteristic of platelets in ANKRD 26-Related Thrombocytopenia seen in peripheral blood smear (PBS).
Down
  1. 2. One of the inclusion in the triad in MYH9-Related Thrombocytopenia Syndromes in which Epstein syndrome lacks.
  2. 3. It is a type of vascular disorder caused by deficiency in Vitamin C and decreased synthesis of collagen with weakening of capillary walls.
  3. 4. A type of deficiency in secondary hemostasis characterized as autosomal recessive trait in which the APTT result is shortened if the plasma is incubated with a surface activating substance.
  4. 6. Hermansky-Pudlak Syndrome and Chediak-Higashi Syndrome are similar in what platelet granule defect?
  5. 9. Henoch-Schonlein Purpura is considered as this type of disease and is characterized by involvement of capillaries with diffuse infiltration of neutrophils, lymphocytes, and macrophages.
  6. 10. It is the most common infectious agent of neonatal thrombocytopenia, which inhibits megakaryocyte and their precursors resulting to impaired platelet production.
  7. 11. It is a vitamin K dependent protein that acts as a cofactor for Protein S.
  8. 13. Result of coagulation screening tests and D-dimer assay in TTP, which differentiates the disorder from DIC.
  9. 15. Large, flat areas of subcutaneous bleeding, resulting in discoloration of the skin that is typically purple or blue-black at first but changes to green or yellow as they heal.
  10. 16. A type of coumadin drug that is water-soluble and is taken orally. It affects the Vitamin-K dependent coagulation factors X, IX, VII, II.
  11. 17. A characteristic pathologic feature of thrombi seen in TTP and are found in multiple organs.
  12. 21. Organ involved in allergic purpura.
  13. 22. Waldenstrom's Purpura primarily affects what gender?
  14. 23. In mixing studies, Factor X is corrected by this substituting reagent.
  15. 26. Nonthrombocytopenic purpura is associated with one of these.
  16. 30. A type of thrombocytosis that results from a primary bone marrow disorder and characterized by an increase number of platelets which is a result of clonal proliferation.
  17. 32. What bone is deficient in TAR?
  18. 34. An intravenous anticoagulant most commonly used in clinical medicine. It is a mucopolysaccharide that acts in conjunction with antithrombin III to inhibit most of serine proteases in the coagulation pathway.
  19. 35. One characteristic symptoms of Wiskott-Aldrich syndrome involving the skin.
  20. 36. Immunization of these type of antibodies from the mother by fetal platelet antigen and placental transfer of maternal antibody.
  21. 37. It is a serine protease inhibitor that neutralized thrombin, Factors IXa, Xa, XIa, XIIa.
  22. 39. It is a type of emboli containing bacteria in blood clots that have broken free of their source and traveled through the blood stream
  23. 40. The enzyme that is defective in Ehlers-Danlos Syndrome
  24. 41. It is a rare type of purpura that develops after one week of transfusion of platelet containing products.
  25. 42. A term characterized by excessive menstrual bleeding. It is also a common symptom in Glanzmann thrombasthenia.
  26. 43. It is the significant problem in TAR where it is presented as low, absent, or immature.
  27. 44. It is a distinct complication in Kasabach-Merritt Syndrome, characterized by a deep vascular mass.
  28. 47. A term characterized by an increase in the circulating platelet count.
  29. 48. A condition results from inherited lack of fibrinogen.
  30. 49. It is distinguished from uncomplicated splenomegaly in that pooling is accompanied by increased destruction of platelets, leukocytes and erythrocytes in association with increased marrow precursors of the deficient and correction of the cytopenia by splenectomy.
  31. 52. These are abnormal globulins formed that precipitates and solidifies
  32. 53. This is where amyloid is commonly seen.
  33. 55. He discovered Factor V deficiency in 1944.
  34. 58. Gender group that is most affected by Wiskott-Aldrich Syndrome
  35. 59. GPIb/IX/V complex deficiency in Bernard-Soulier Syndrome is associated in what mechanism of platelet function?
  36. 60. The primary distinction or behavior of platelets in Kasabach-Merritt Syndrome.
  37. 63. In Secondary thrombocytosis, TPO levels are usually?
  38. 65. One clinical manifestation of platelet and vascular disorder that is characterized by small, pin-point red rashes.
  39. 67. Mucosal bleeding, visual changes, and neurological symptoms in Hyperviscosity syndrome are generally called?
  40. 68. In NAITP, what is the status of the platelets of the affected newborns at one week after birth.
  41. 69. Platelet lifespan in ITP.
  42. 72. It is a type of purpura most commonly seen in older individuals.
  43. 75. It is a type of collagen primarily involved in Osteogenesis Imperfecta.