Across
- 1. fibrosis a mutation in a gene that changes a protein that regulates the movement of salt in and out of cells; characterized by the production of thick and sticky mucus.
- 5. blindness an abnormal condition caused by an X-linked recessive allele and characterized by the inability to clearly distinguish different colours of the visible light spectrum.
- 8. disease caused by a genetic defect on chromosome 4; the defect causes a part of DNA, called a CAG repeat, to occur many more times than it is supposed to.
- 10. allele an allele that has an effect on the phenotype only when present in the homozygous state.
- 12. genes chromosomes that do not determine sex.
- 14. a chemical or physical agent that interacts with DNA and causes a mutation.
- 17. the genetic constitution of an organism.
- 18. one of two haploid reproductive cells, egg or sperm, whose union is necessary in sexual reproduction to produce a diploid zygote.
Down
- 2. alleles two alleles at a particular locus that have different effects and are distinguishable in a heterozygous individual (e.g. AB blood groups).
- 3. a sex-linked inheritable disease characterized by loss or impairment of the normal clotting ability of blood, so that a minor wound may result in fatal bleeding.
- 4. inheritance traits controlled by genes located on one sex chromosome but not the other.
- 6. grid (or Punnett square) a tool that helps to show all possible allelic combinations of gametes in a cross of parents with known genotypes in order to predict the probability of their offspring possessing certain sets of alleles.
- 7. the physical and physiological traits of an organism.
- 9. cells have one chromosome of each pair (have one full set of the chromosomes that are found in its species).
- 11. a hereditary unit consisting of a sequence of DNA that occupies a specific location on a chromosome and determines a particular characteristic in an organism.
- 13. one of the possible alternatives of a gene, occupying a specific position on a chromosome, that controls the same trait.
- 15. alleles the allele that is fully expressed in the phenotype of a heterozygote.
- 16. the diploid product of the fusion of haploid gametes (a fertilized egg).
