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Across
  1. 6. Region where substrate binds on enzyme
  2. 7. Neutral species with unpaired electron
  3. 8. Adding acyl group to aromatic compound
  4. 13. Breakdown of molecules to release energy
  5. 14. Positively charged carbon species
  6. 17. Short-lived species during reaction
  7. 19. Organic molecule assisting enzyme
  8. 20. Building complex molecules from simpler ones
  9. 21. Minimum energy required to react
Down
  1. 1. Site other than active site for regulation
  2. 2. Non-protein helper for enzyme activity
  3. 3. Total of all chemical reactions in organism
  4. 4. Molecule acted on by enzyme
  5. 5. Substance reducing enzyme activity
  6. 9. Adding alkyl group to aromatic compound
  7. 10. Atom or molecule donating electrons
  8. 11. Protein acting as biological catalyst
  9. 12. Negatively charged carbon species
  10. 15. Highest energy point during reaction
  11. 16. Atom or molecule seeking electrons
  12. 18. Step-by-step pathway of reaction