Acute Rheumatic Fever and Rheumatic Heart Disease

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Across
  1. 2. infection by group A B-hemolytic streptococcus is the initial injury before RHD develops.
  2. 8. is the exotoxin and hemolytic factor against which serum antibodies are measured.
  3. 9. initiated from M proteins of certain streptococci strains react with glycoproteins in the heart.
  4. 12. can occur after recurrent or acute untreated rheumatic fever.
  5. 13. may require corticosteroids diuretics.
  6. 14. percent of individuals with rheumatic fever develop Rheumatic Heart Disease (RHD).
Down
  1. 1. penetrating the myocardium causes fibrin deposits to erode valvular tissue and the chordae tendinae cordis.
  2. 3. throat cultures are one method for diagnosis confirmation for acute rheumatoid fever (ARF).
  3. 4. are used as anti-inflammatory agents for carditis.
  4. 5. conduction defects are associated with rheumatic heart disease (RHD.
  5. 6. inflammation from the central lesion of RHD involves the endocardium.
  6. 7. is the most critical illness form of acquired heart disease in children and young adults living in developing countries.
  7. 9. molecules specific to group A B-hemolytic streptococcus direct the immune response of acute rheumatic fever.
  8. 10. repair of damaged heart valves may be required for some instances of RHD.
  9. 11. rheumatic fever in over 50% of child cases may need preventative antibiotic therapy for as long as 5 years.