Across
- 4. : Type of antibody assay recommended for annual screening.
- 8. : Descriptor preceding nephropathy in severe renal disease.
- 9. : Finding that should always be screened for in every seropositive dog.
- 12. : European breed with an unusually high seroprevalence.
- 13. : Bacterial genus responsible for Lyme borreliosis.
- 15. : Outer surface protein upregulated during tick feeding and mammalian infection.
- 17. : Tick preventive that repels and prevents attachment but must never be used in cats.
- 18. : Injectable antimicrobial shown to be comparable to doxycycline in experimental infection.
- 19. : Preferred immunosuppressive drug for severe immune-complex glomerulonephritis.
- 21. : Development of detectable antibodies after exposure.
- 23. : Preventive measure unanimously recommended regardless of vaccination status.
- 24. : Histologic lesion described at experimental tick bite sites.
- 27. : Most common clinical manifestation of Lyme borreliosis in dogs.
- 29. : Outer surface protein expressed in the tick midgut before transmission.
- 30. : Renal lesion associated with immune-complex deposition.
- 31. : Common systemic clinical sign accompanying Lyme arthritis.
- 35. : Tetracycline considered an alternative to doxycycline.
- 37. : Isoxazoline effective against Ixodes transmission.
- 39. : Acceptable alternative antimicrobial for Lyme borreliosis.
- 40. : Species responsible for canine Lyme disease in North America.
- 41. : Severe renal manifestation putatively associated with Lyme borreliosis.
- 44. : Principal Ixodes vector in Europe.
- 45. : Typical presenting clinical sign in affected dogs.
Down
- 1. : Mild enlargement of lymph nodes may accompany acute disease.
- 2. : Characteristic of most healthy seropositive dogs.
- 3. : Type of C6 assay whose routine use remains controversial.
- 5. : Type of pathogen transmission occurring between tick life stages.
- 6. : Tick genus responsible for transmitting Borrelia burgdorferi.
- 7. : Possible explanation for recurrence after successful treatment.
- 10. : Mechanism believed to contribute to Lyme nephritis.
- 11. : Main North American Ixodes vector.
- 12. : Possible coinfection that may complicate interpretation of Lyme disease.
- 14. : Breed group overrepresented among dogs with suspected Lyme nephritis.
- 16. : Corticosteroid that may be added for rapidly progressive glomerular disease.
- 18. : Peptide used in serologic testing to detect natural exposure to Borrelia.
- 20. : General term for products used to prevent tick infestation.
- 22. : Variable major protein-like sequence expressed; antigen used in modern serologic assays.
- 25. : Tick-borne coinfection commonly covered by doxycycline.
- 26. : Clinical recurrence that requires reconsideration of differential diagnoses.
- 28. : First-line antimicrobial recommended for canine Lyme arthritis because it also covers common tick-borne coinfections.
- 32. : Important explanation for persistent or atypical clinical signs.
- 33. : Another oral isoxazoline used for tick prevention.
- 34. : Another important tick-borne pathogen included in differential diagnoses.
- 36. : Topic for which the panel did not reach full consensus.
- 38. : Describes a dog with detectable antibodies against Borrelia.
- 42. : Histologic lesion observed experimentally after infection.
- 43. : Isoxazoline that rapidly kills attached ticks.