Adaptive Immunity

1. Effector Th1 CD4 cell subset produce IFN gamma, activate macrophages and stimulate IgG production.
5. CD8+ cells recognize intracellular antigens presented on ________ surface molecule.
7. Helper T cells that prime and coordinated CD8 and B cells.
8. Effector Th2 CD4 cell subset that produce IL-4 and IL-13 and activates alternative macrophages that dampen inflammatory responses.
11. Changing of the immunoglobulin (Ig) class produced by the B cell.
12. Antibody coated infected cells are recognized by NK cells and kill.
17. Antibodies that interact with virus at the host receptor site and blocks viral entry.

2. Antibody mediated phagocytosis of microbes.
3. _______ cells produce antibodies that mediate protective immunity.
4. Cells that present antigens & prime adaptive response.
5. Hallmark of adaptive immunity.
6. Immunity type mediated by B cells.
9. Is a major antiviral immunoglobulin
10. CD4+ cells recognize extracellular antigens presented on ___________ surface molecule.
11. Antibodies that perform effector functions at sites distant from the production site.
13. Activated CD8+ cells that produce Perforin/Granzyme to kill infected cells.
14. Secretory antibody that have access to mucosal surfaces.
15. Presentation of ______ occurs in lymph nodes and mucosa.
16. T and B cells receptor ________ emerge from random gene rearrangement and selection.