Adaptive Immunity

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Across
  1. 2. The process of destroying B and T cells that react to self antigens
  2. 5. First Ab produced in response to infection;Pentamer
  3. 6. disruption of cell by complement reactive protein attracts phagocytic & other defense immune system cells
  4. 7. 2nd exposure to same Ag, the response is rapid & results in high Ab titer
  5. 9. Specific antibody and lymphocyte response to an antigen
  6. 10. Proteins made in response to an antigen
  7. 12. Allergic reactions; lysis of parasitic worms;Monomer
  8. 13. T cytotoxic cells (destroy deformed/infected cells)
  9. 14. mature in bone marrow; hangs out in germinal center in cortex
  10. 16. carried out by antibodies circulating in the blood. Antibodies are produced by B lymphocytes that have matured into plasma cells
  11. 20. develop in bone marrow or in fetal liver
  12. 25. cells suppress T cells against self subset of CD4 TH cells formerly called T suppressor cells
  13. 26. stimulates T-h cells
  14. 29. coating antigen with antibody enhances phagocytosis
  15. 30. first contact with Ag is characterized by IgM followed by IgG
  16. 31. B cells becomes activated when an Ag reacts with specific receptors on its surface
  17. 32. activates T-h, B, T-c, and NK cells
Down
  1. 1. mature in thymus;hangs out in medulla
  2. 3. enhances phagocytosis & reduces number of infectious units to be dealt with
  3. 4. In secretions (tears,colostrum, saliva, mucus);Dimer
  4. 8. Antibody that remains associated with the cytoplasmic membrane of the B lymphocyte
  5. 11. On B cells, initiate immune response;Monomer
  6. 13. induce migration of leukocytes to infection
  7. 15. blocks adhesion of bacteria & viruses to mucosa
  8. 17. in all cells. Accepts or rejects ag as compatible or not.Attaches to non compatible ag and presents it to T cell
  9. 18. digest antigen; can be any type of phagocyte
  10. 19. Main class of Ab in blood (80% of serum antibodies);monomer
  11. 21. T helper cells(surface antigen)
  12. 22. immunity carried out by T lymphocytes and occurs at the cellular level
  13. 23. cells that kill/attack
  14. 24. A substance the body identifies as foreign and to which it produces specific antibodies or sensitized Tcells
  15. 27. small molecule that can act as an antigen if it binds to a larger protein molecule
  16. 28. destroy t-h cells & impairs humoral & cell mediated immunity