Addiction + Biology

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Across
  1. 2. Researcher who used brain imaging and Ritalin studies
  2. 5. Researcher who reviewed adoption studies in 2008
  3. 7. Reduction in receptor numbers after repeated stimulation
  4. 8. Gene linked to dopamine receptor A1 variant
  5. 11. Researcher who found high concordance in MZ twins
  6. 15. Non-genetic influences interacting with genes
  7. 16. STUDY, Study comparing adopted children to biological parents
  8. 18. Researcher associated with the Virginia twin study
  9. 19. Process by which pleasurable behaviours are strengthened
  10. 20. Drug used to investigate dopamine receptor availability
  11. 21. PATHWAY, Alternative name for the mesolimbic pathway
  12. 24. Reduced effect requiring increased substance use
  13. 25. Toxic intermediate product in alcohol metabolism
  14. 27. Section evaluating competing explanations
  15. 28. Neurotransmitter central to the reward pathway
  16. 29. CORTEX, Brain region involved in impulse control and relapse
  17. 30. Idea that addiction results from genes and environment working together
Down
  1. 1. Continued engagement despite reduced pleasure
  2. 3. Strength of biological explanation in reducing blame
  3. 4. Extent to which variation is due to genes
  4. 6. Enzyme converting ethanol into acetaldehyde
  5. 9. Proteins that dopamine binds to
  6. 10. Explanation involving culture and social status
  7. 12. Biological transmission of traits
  8. 13. First stage of addictive behaviour
  9. 14. STUDY, Study comparing identical and non-identical twins
  10. 17. Brain changes following repeated substance use
  11. 22. Enzyme converting acetaldehyde into acetate
  12. 23. Dopamine pathway strongly implicated in addiction
  13. 26. Chemical produced after acetaldehyde is broken down