AMR

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Across
  1. 1. gram+ skin commensal of many animals and humans; acquired resistance gene encoding for new PBP2A with low affinity to most β-lactams
  2. 3. treat the earliest and for the shortest time possible
  3. 5. hygiene, management, vaccination.....
  4. 6. _______ resistance: naturally acquired trait; species or genus specific
  5. 7. use of highest possible dose
  6. 8. ______ resistance: by mutation in the existing DNA of the organism; by acquisition of new DNA via transformation, transduction or conjugation
Down
  1. 1. gram+ skin commensal of dogs; some strains are MDR
  2. 2. administer the drug at regular intervals
  3. 4. the bacterial ability to survive antimicrobial therapy and cause therapeutic failure
  4. 9. Gram- bacteria producing an enzyme that can hydrolyze/inactivate most β-lactams, except carbapenems; higher risk of food borne transmission