Anemia and Hematology

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Across
  1. 4. White blood cells that are typically increased in the presence of allergies or parasitic infections.
  2. 8. A lab test used to assess iron stores; it is low in iron deficiency but elevated in inflammatory anemia.
  3. 9. A measurement of how quickly new red blood cells are being made by the bone marrow.
  4. 11. A term used to describe a variation in the size of red blood cells.
  5. 12. Red blood cells that have lost their shape and become spherical, often seen in autoimmune hemolytic anemia.
  6. 16. A type of macrocytic anemia caused specifically by the loss of intrinsic factor in the stomach.
  7. 18. Irregular red blood cell fragments that are specific to mechanical damage.
  8. 19. A hormone (erythropoietin) that tells the bone marrow to produce more red blood cells.
  9. 20. A reduction in all three blood cell lines (RBCs, WBCs, and platelets), which is a hallmark of aplastic anemia.
  10. 21. The most common white blood cell and the "first responders" that fight bacterial infections.
Down
  1. 1. Cellular fragments that remain in circulation for about 10 days and are necessary for clotting.
  2. 2. A term used to describe a variation in the shape of red blood cells.
  3. 3. A hormone that induces iron restriction and is involved in the pathophysiology of anemia of chronic disease.
  4. 5. Inclusion bodies formed in red blood cells during an "oxidative challenge" in patients with G6PD deficiency.
  5. 6. The process by which red blood cells, white blood cells, and platelets are formed.
  6. 7. The most useful test for detecting antibodies attached to red cell membranes.
  7. 10. Red blood cells that comprise roughly 40% of blood volume and function to carry oxygen to the tissues.
  8. 13. A clinical manifestation of iron deficiency involving the craving to eat unusual substances like ice or clay.
  9. 14. A component of the CBC that indicates the range in sizes of red blood cells.
  10. 15. A lab index used to determine if red blood cells are macrocytic (large) or microcytic (small).
  11. 17. A specific type of stippling seen on a peripheral smear in cases of lead poisoning.
  12. 20. The fluid component of blood comprised of water, ions, proteins, nutrients, and wastes.