Anti-Cytokine Therapy

Edit Answers
12345678910111213141516
Across
  1. 4. drug that binds BAFF (B cell activating factor) to prevent B cell survival
  2. 6. IL-1 receptor antagonist (recombinant endogenous protein)
  3. 10. monoclonal antibody that binds IL-17A
  4. 11. monoclonal antibody against IL-17A
  5. 13. antibody to 17A receptor; suicide warning
  6. 14. monoclonal antibody to IL-6 receptor
  7. 15. monoclonal antibody that targets the p19 subunit of IL-23; binds cytokine
  8. 16. a soluble fusion protein that binds the TNF alpha receptor
Down
  1. 1. a monoclonal antibody that binds TNFalpha in both soluble and transmembrane form
  2. 2. a monoclonal antibody that binds TNFalpha in both soluble and transmembrane form
  3. 3. monoclonal antibody that targets the p19 subunit of IL-23; binds cytokine
  4. 5. a monoclonal antibody that binds TNFalpha in both soluble and transmembrane form
  5. 7. monoclonal antibody that targets the shared p40 subunit of both IL-12 and IL-23
  6. 8. monoclonal antibody that binds IL-6 receptor; also given emergency approval for use against COVID-19 to treat cytokine storm
  7. 9. Fab fragment of humanized antibody that binds TNF alpha
  8. 12. biologic agent that blocks costimulation of T cells by conjugation IgG to CTLA-4