Antibodies

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4. A chemical message from one type of cell to another.
8. Action of antibodies: to aggregate around an antigen, forming clumps.
9. The arms of the antibody, which have hypervariable regions to fit thousands of antigens.
14. Where B-cells go to mature in the lymphatic system.
16. Cell receptor on a T-cell that triggers its kill-mode when an antigen on MHCI binds with it.
17. Interferon type produced by lymphocytes and macrophages to warn of viral infection.
18. An antigen that will provoke an immune response.
19. Where T-cells go to mature in the lymphatic system.
21. Coming from inside (ex. a threat like viral infection or cancer).
22. Action of antibodies: to crosslink with other antibodies, forming large clumps and neutralizing toxins.
24. Autoantigen in a patient with lupus (SLE).
25. Interferon type produced by T-cells to warn of viral infection.
26. Local reaction to an allergen - edema and inflammation.
27. Cell receptor on a T-cell that triggers its differentiation into a helper cell when it connects with an antigen on MHCII.
28. A molecule in self tissues that are similar to a pathogenic antigen - provoking immune attack.
29. A role of antibodies: to cover an attachment spike of a pathogen.
31. A larger molecule that can attach to haptens, making them more noticeable by immune cells.
34. Coming from outside (ex. a threat like invading bacteria or protozoa).

1. The body/stem of the antibody, which phagocytes use to recognize each other and where complement proteins can bind.
2. Systemic reaction to an allergen - inflammation, bronchoconstriction, urticaria, circulatory shock, and airway obstruction.
3. Interferon type produced by fibroblasts and epithelial cells to warn of viral infection.
5. One role of antibodies: to cover bacteria and allow them to be recognized and eaten by phagocytes.
6. Central part of bone where all white and red blood cells are generated as stem cells.
7. A chemokine used by T-cells to communicate with B-cells.
10. Foreign molecules that are too small to create an immune response.
11. Autoantigen in a patient with multiple-sclerosis (insulation of nerves).
12. Another word for an antibody: 4 polypeptide chains connected by disulfide bonds.
13. Type of immunity provided by B-cells and antibodies.
15. Binding site on an antigen where antibodies attach.
16. Moving in response to a chemical attractant/repellant.
20. A dimer in mucous and serous secretions, blood, breastmilk and other fluids.
23. A complex antibody synthesized by B-cells after encounter with an antigen, a pentamer.
27. A chemical message from one WBC to another WBC.
30. Antibody expressed on the surface of all B-cells.
32. Antibody that binds to mast cells and basophils, starting an allergic response.
33. Most common antibody (80% of all antibodies), a monomer produced for first response to infection.