Across
- 2. HVA Ca+ channel blocker; used for focal seizures and neuropathic pain
- 5. LVA Ca+ channel blocker; absence epilepsy in children, recommended for girls in child bearing age, cause much less CNS depression than other AED's; associated with blood disorders
- 7. VGNa+C blocker, HVA Ca+ channel blocker; commonly prescribed AED, low teratogenicity
- 8. VGNa+Channel blocker; LVA Ca+ channel blocker & GABA transaminase inhibitor; also used for migraines and mania; very teratogenic
- 9. First choice anticonvulsant
- 11. Na+ channel blocker used to treat status epilepticus (IV) and all other seizures besides Absence seizures
Down
- 1. Synaptic vesicle protein 2A protein binding; used in focal seizures; favoured for women of childbearing age; low teratogenicity
- 3. VGNa+C blocker, HVA Ca+ blocker, GABAaR, adjunct therapy used for focal & tonic- clonic epilepsy
- 4. HVA Ca+ channel blocker; used as an alt. to BDZ for anxiety; used for focal seizures and neuropathic pain
- 6. Na+ channel blockers; first line treatment for patients with temporal lobe epilepsy (most common type); also used to treat neuropathic pain; caution in patients with liver & blood disorders as they're powerful CYP inducers
- 10. GABAa positive modulators; adjunct anti-epileptic medication for children; fast acting, emergency treatment for acute seizures and status epilepticus