Antivirals

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Across
  1. 3. influenza A, inhibitor of viral coat assembly and neuraminidase
  2. 5. inhibits virus attachment (fusion) to CD4
  3. 9. nucleoside RT inhibitor, treat HIV in combination
  4. 12. viral DNA polymerase inhibitors, treat herpes, also famciclovir
  5. 13. antibodies vs viruses
  6. 14. anti-covid drug, nirmatrelvir + ritonavir, protease inhibitor
  7. 15. non-nucleoside RT inhibitor, treat HIV in combination and Hep B
  8. 17. viral DNA polymerase inhibitors, treat cytomegalovirus, also cidofovir
  9. 18. anti-covid drug, prevents organ dysfunction and lung injury from inflammation, lots of side effects
Down
  1. 1. enveloped RNA virus, transmitted through airborne droplets, infected surfaces, and fecal oral route, affects respiratory system
  2. 2. used in combination with RT inhibitors (HAART), inhibit synthesis and cleavage of new viral particles
  3. 4. nucleoside RT inhibitor, treat Hep B, also entecavir and tenvofir
  4. 6. nucleoside RT inhibitor, treat HIV in combination
  5. 7. nucleoside RT inhibitor, treat HIV in combination
  6. 8. induce enzymes to inhibit translation of viral mRNA into protein and/or destroying RNA, thereby halting replication
  7. 10. anti-covid drug, nucleoside RT inhibitor
  8. 11. anti-covid drug, RNA polymerase inhibitor, improves pulmonary function and reduces viral load
  9. 16. target for spike protein of SARS-COV-2