A&P 1, Chapter 21. The lymphatic and immune system

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Across
  1. 5. ability of B cells to change the class of antibody they produce without altering the specificity for antigen
  2. 6. binding of processed antigen to the protein-binding cleft of a major histocompatibility complex molecule
  3. 8. cells that secrete cytokines that induce B cells to differentiate into antibody-secreting plasma cells
  4. 10. clusters of rapidly proliferating B cells found in secondary lymphoid tissues
  5. 11. vessels containing unique endothelial cells specialized to allow migration of lymphocytes from the blood to the lymph node
  6. 12. enhancement of phagocytosis by the binding of antibody or antimicrobial protein
  7. 13. selection against thymocytes in the thymus that react with self-antigen
  8. 14. molecule in NK cell and cytotoxic T cell granules that form pores in the membrane of a target cell
  9. 15. soluble, short-range, cell-to-cell communication molecule
  10. 16. early induced proteins made in virally infected cells that cause nearby cells to make antiviral proteins
  11. 17. enzymatic cascade of constitutive blood proteins that have antipathogen effects, including the direct killing of bacteria
Down
  1. 1. soluble, long-range, cell-to-cell communication molecule
  2. 2. apoptosis-inducing substance contained in granules of NK cells and cytotoxic T cells
  3. 3. selection of thymocytes within the thymus that interact with self, but not non-self, MHC molecules
  4. 4. molecule expressed on cytotoxic T cells and NK cells that binds to the fas molecule on a target cell and induces it do undergo apoptosis
  5. 7. protein antibody; occurs as one of five main classes
  6. 9. first exposure to an antigen
  7. 15. stimulating growth of lymphocytes that have specific receptors