Across
- 2. found on macrophages, dendritic cells, and B cells, it binds to CD4 molecules on T cells
- 4. apoptosis-inducing substance contained in granules of NK cells and cytotoxic T cells
- 6. molecule in NK cell and cytotoxic T cell granules that form pores in the membrane of a target cell
- 8. early induced proteins made in virally infected cells that cause nearby cells to make antiviral proteins
- 10. found on most cells of the body, it binds to the CD8 molecule on T cells
- 12. selection against thymocytes in the thymus that react with self-antigen
- 17. clusters of rapidly proliferating B cells found in secondary lymphoid tissues
- 18. cells that secrete cytokines that enhance the activity of macrophages and other cells
- 19. main blood antibody of late primary and early secondary responses; passed from carrier to unborn child via placenta
- 21. unencapsulated patches of lymphoid tissue found throughout the body
Down
- 1. vasoactive mediator in granules of mast cells and is the primary cause of allergies and anaphylactic shock
- 3. soluble, long-range, cell-to-cell communication molecule
- 5. T lymphocytes with the ability to induce apoptosis in target cells
- 7. enhancement of phagocytosis by the binding of antibody or antimicrobial protein
- 9. stimulating growth of lymphocytes that have specific receptors
- 11. relatively slow but very specific and effective immune response controlled by lymphocytes
- 13. molecule recognized by the receptors of B and T lymphocytes
- 14. ability of B cells to change the class of antibody they produce without altering the specificity for antigen
- 15. cells that secrete cytokines that induce B cells to differentiate into antibody-secreting plasma cells
- 16. immunity developed from an individual’s own immune system
- 20. soluble, short-range, cell-to-cell communication molecule
