Across
- 1. Lymphatics located in subcutaneous tissues
- 3. _____ tonsils are located in the posterior oral cavity
- 4. Substances that induce fever
- 9. Molecule on B cells that binds antigen
- 12. Tonsil located in the nasopharynx
- 15. Trunks draining lower limbs and pelvic organs
- 16. Keratinized epithelial barrier protecting against pathogens
- 17. Antibody region responsible for antigen binding
- 19. Age-related shrinkage of the thymus
- 20. Lymphoid nodules in the pharynx intercepting pathogens
- 22. Molecules that present antigen fragments on cell surfaces
- 24. The cisterna _____ collects lymph from intestinal trunks
- 25. Another class of interferon proteins
- 27. Physical structures preventing pathogen entry
- 29. Immune cells responsible for adaptive immunity
- 31. Lymphatic vessels occur in most vascularized _____
- 32. Natural _____ cells destroy infected cells
- 33. Pyrogens produced by immune cells
- 35. Inner lymph node region containing plasma cells
- 36. Chemical mediator released by mast cells
- 37. Expansion of lymphocytes after antigen recognition
- 39. Network of vessels that transports lymph toward the heart
- 41. Cells that perform phagocytosis of debris and pathogens
- 43. Heavy _____ determine antibody class
- 44. Large lymphatic channels receiving lymphatic trunks
- 45. Antiviral proteins produced during viral infection
- 48. Membrane attack _____ forms pores in pathogens
- 52. T cells that suppress immune responses
- 55. Tonsils located at the base of the tongue
- 58. The _____ duct drains most of the body
- 59. Process of B cells becoming plasma cells
- 61. Antibody region interacting with immune cells
- 62. Trunks that drain the upper limbs
- 63. Outer region of a lymph node containing B cell follicles
- 64. Spread of cancer cells through lymphatic drainage pathways
- 67. Adaptive immunity provides highly _____ antigen targeting
- 71. Anchoring _____ prevent collapse of lymphatic capillaries
- 74. Skeletal _____ contractions help push lymph through vessels
- 75. Tight _____ prevent microbial penetration between cells
- 77. Sticky secretion that traps pathogens
- 79. One class of interferon proteins
- 82. Elevated body temperature caused by pyrogens
- 83. Cells that engulf microbes during innate immunity
- 84. Thin endothelial walls increase vessel permeability
- 85. Lymphatics found along major arteries and veins
- 86. Programmed cell death induced by cytotoxic T cells
- 89. Process of displaying antigens to T cells
- 90. Interstitial fluid that enters lymphatic vessels
- 91. Fluid accumulation causing tissue enlargement
Down
- 2. Y-shaped proteins produced by plasma cells
- 5. Immune response to tissue injury or infection
- 6. Increased vessel _____ allows immune cells to exit blood
- 7. Major antigen-presenting cells found in tissues
- 8. The _____ lymphatic duct drains the right upper quadrant
- 10. Pressure changes during _____ assist lymph movement
- 11. Trunks draining thoracic organs
- 13. Major lymphatic vessels draining large body regions
- 14. Interferon type that activates immune cells
- 18. Small bean-shaped organs that filter lymph
- 20. Primary lymphoid organ responsible for T cell maturation
- 21. Germinal _____ are sites of rapid B cell proliferation
- 23. Complement pathway activated by antigen-antibody complexes
- 26. Intestinal lymphoid aggregates called _____ patches
- 28. Widening of blood vessels during inflammation
- 30. Complement pathway activated directly by pathogen surfaces
- 31. Hormones secreted by the thymus regulating T cell development
- 34. Flexible region allowing antibody movement
- 38. Type of immunity present at birth
- 40. T cells that destroy infected or abnormal cells
- 42. Immunity that develops after antigen exposure
- 43. Structures that move mucus out of respiratory tract
- 46. B cell clusters found in the lymph node cortex
- 47. One classic sign of inflammation
- 49. Proteins that create pores in target cells
- 50. Skin secretion containing antimicrobial compounds
- 51. Smallest lymphatic vessels that begin as blind-ended sacs
- 53. Molecules capable of triggering an immune response
- 54. _____ lymphoid tissue contains scattered immune cells
- 56. Tissue that replaces thymic tissue with aging
- 57. Lymph node region containing T lymphocytes
- 60. Structures that prevent backward movement of lymph
- 65. Lymphatic trunks draining head and neck
- 66. Sensory response associated with inflammation
- 68. Cells that produce and secrete antibodies
- 69. Surface folds in tonsils that trap pathogens
- 70. Group of plasma proteins involved in immune defense
- 72. Lymphatic capillaries have a larger _____ than blood capillaries
- 73. Enzymes that trigger apoptosis in infected cells
- 76. Pyrogens produced by pathogens
- 77. Abbreviation for mucosa-associated lymphoid tissue
- 78. Cell destruction caused by membrane attack complexes
- 80. T cells that activate other immune cells
- 81. Disease-causing microorganisms detected by the immune system
- 87. Oily skin secretion that creates acidic environment
- 88. Long-term immune protection after infection