apoptosis

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Across
  1. 4. Regions within caspases 2,8,9,10
  2. 7. Phospholipid translocated from membrane's inner to outer leaflet during apoptosis
  3. 8. Membrane-anchored FasL on the surface of an adjacent cells causes ..... of the Fas receptor
  4. 11. Parametr of apoptotic cells measured during flow cytometry
  5. 15. Proapoptotic protein regulated (within gene promoter) by p53
  6. 17. Characteristic appearance of membranes during apoptosis
  7. 18. Tumor necrosis factor receptor
  8. 19. Characteristic pattern of DNA in apoptotic cells
  9. 21. Passive pathological process induced by cellular injury
Down
  1. 1. Adaptor molecules of TNFR
  2. 2. Family of proteins that binds to phosphatidylserine in outer membrane leaflet (due to apoptosis)
  3. 3. Substance released by T cytotoxic cells to acivate cascade of cytokines
  4. 5. Complex of Fas receptor(trimer), FADD and caspase 8
  5. 6. Cytokines released by phagocytic cells that degrades an apoptotic cell.
  6. 7. Tumor supressor protein
  7. 9. Adaptor protein activated by cytochrome c
  8. 10. Caspases 3,6,7
  9. 12. Method in which terminal uridine deoxynucleotidyl transferase nick end labeling is used
  10. 13. Form of inactive caspases
  11. 14. State of chromatin found in nucleus in apoptosis
  12. 16. Exits mitochondria through a channels created by a Bax protein
  13. 20. Prodeath member of Bcl-2 family
  14. 22. Fas ligand expressed by T-cytotoxic cells