Across
- 2. There are 3 types of antigen-presenting cells: macrophages, ______ cells, and B cells.
- 4. B cell antigen receptors recognise unique _____ on the surface of antigens.
- 6. ______ lymphoid organs/tissues include the lymph nodes and spleen.
- 9. Antibodies can stimulate natural _____ cells to release perforin and granzymes.
- 11. Only _____-presenting cells have MHC II molecules on their surfaces.
- 13. ______ are classified on the basis of their Fc regions.
- 14. Antibodies can activate ______ proteins which, when activated, will form pores in the cell membrane called MACs (Membrane Attack Complexes).
- 16. When activated, B cells multiply. Some of the B cell clones differentiate into ____ cells, which produce soluble antibodies.
- 17. _______ lymphoid organs/tissues refer to the bone marrow and the thymus.
Down
- 1. Every immunoglobulin has a fragment antigen-binding and a fragment ______ region.
- 3. Each immunoglobulin has ____ antigen-binding sites.
- 5. When antibodies cross-link soluble antibodies, they _____ out of solution.
- 7. T cells recognise antigen __________ displayed by self cells, while B cells recognise intact antigens on foreign cells.
- 8. _____ are the most common antibodies and are the only antibodies small enough to cross the placenta.
- 10. MHC genes code for ____ antigens which are attached to the surface of body cells.
- 12. B cells mature in the bone marrow while T cells mature in the _____.
- 15. Antibodies can act as _______ to enhance phagocytosis by binding to the Fc receptors on phagocytes such as macrophages.
