B Cells and T Cells

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Across
  1. 2. There are 3 types of antigen-presenting cells: macrophages, ______ cells, and B cells.
  2. 4. B cell antigen receptors recognise unique _____ on the surface of antigens.
  3. 6. ______ lymphoid organs/tissues include the lymph nodes and spleen.
  4. 9. Antibodies can stimulate natural _____ cells to release perforin and granzymes.
  5. 11. Only _____-presenting cells have MHC II molecules on their surfaces.
  6. 13. ______ are classified on the basis of their Fc regions.
  7. 14. Antibodies can activate ______ proteins which, when activated, will form pores in the cell membrane called MACs (Membrane Attack Complexes).
  8. 16. When activated, B cells multiply. Some of the B cell clones differentiate into ____ cells, which produce soluble antibodies.
  9. 17. _______ lymphoid organs/tissues refer to the bone marrow and the thymus.
Down
  1. 1. Every immunoglobulin has a fragment antigen-binding and a fragment ______ region.
  2. 3. Each immunoglobulin has ____ antigen-binding sites.
  3. 5. When antibodies cross-link soluble antibodies, they _____ out of solution.
  4. 7. T cells recognise antigen __________ displayed by self cells, while B cells recognise intact antigens on foreign cells.
  5. 8. _____ are the most common antibodies and are the only antibodies small enough to cross the placenta.
  6. 10. MHC genes code for ____ antigens which are attached to the surface of body cells.
  7. 12. B cells mature in the bone marrow while T cells mature in the _____.
  8. 15. Antibodies can act as _______ to enhance phagocytosis by binding to the Fc receptors on phagocytes such as macrophages.