Across
- 4. key players to adaptive (acquired) immunity; 20-40% of all leukocytes (WBC's)
- 6. ____ cells "record" information to fight pathogen if it comes back
- 7. ____ response is when the antibodies, rather than the B cells themselves, defend against pathogens
- 10. T-cells have T-cell ____
- 11. _____ cells are a subset leading to a humoral response
- 13. ____ cells actively secrete antibodies
- 14. _____ immunity is developed when the innate immune system cannot handle getting rid of the pathogen; it is a very specific response to a pathogen and is slower to develop than innate immunity
- 17. ____ cells are a subset against primarily intracellular pathogens
Down
- 1. B-cells have ____ receptors
- 2. ____ T-cells recognize antigen presented via MHC 11 or MHC 1 and express CD4 or CD8
- 3. _____ T-cells recognize antigen presented via MHC1 and express CD8; directly destroy cells they recognize, which re often virus-infected cells
- 5. _____ T cells recognize antigen presented via MHC 2 and also express CD4
- 8. Each ____ is a y-shaped protein molecule with two identical heavy chains and two identical light chains
- 9. the smallest accessible part of an antigen that binds to an antigen receptor
- 12. Binding of a BCR to an antigen is an early step in B-cell activation, as before this cells are termed ____
- 15. _____ are substances that can elicit a response from a B or T cell
- 16. ____ cells are a subset that contribute to protection at mucosal surfaces