BIO 202 Ch 13: Host Defenses II - Adaptive Defenses and Immunization

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Across
  1. 2. cell type which directly destroys cells it recognizes.
  2. 3. B cell type which actively secretes antibodies (Ab).
  3. 8. artificial active immunity.
  4. 10. acquired immunity is ___ than innate immunity.
  5. 14. antigen receptor found on a T cell.
  6. 15. passive immunity is most useful in individuals who are classified as this.
  7. 17. Edward ___ used cowpox to prevent smallpox.
  8. 18. breast milk is a vector for this kind of passive immunity.
  9. 19. lymphocytes which express both CD4 and CD8. frequently help limit chronic inflammatory diseases.
  10. 21. synonymous with Ig. a soluble form of BCR.
  11. 22. recognizes antigen presented by MHC II and expresses CD4.
  12. 24. lymph nodes and this are peripheral lymphoid organs where mature T cells reside.
  13. 26. natural active immunity comes about as a result of this.
  14. 28. bridge binding the constant regions of a BCR or a TCR.
  15. 29. the number of heavy chains on a BCR, which is equal to the number of light chains.
  16. 32. T cell type which conducts the immune system orchestra.
  17. 33. recognizes antigen presented by MHC I and expresses CD8.
  18. 36. status of a lymphocyte prior to its binding with an antigen.
  19. 37. region which accounts for BCR specificity. formed by both light and heavy chains.
  20. 39. B cell type which records information about an antigen for future defense.
  21. 41. both B and T cells are produced here. B cells mature here.
  22. 42. the type of leukocyte involved in acquired immunity.
  23. 43. B cells use this glycoprotein to present antigen fragments, thereby acting as an APC.
  24. 44. region of an antigen which binds to an antigen receptor.
Down
  1. 1. Latin name for livestock animal which is the origin of the word vaccine.
  2. 2. region which is structurally similar across all BCRs.
  3. 4. B cells, macrophages, and dendritic cells can all act as this.
  4. 5. the tips of alpha and beta chains form this region on a TCR.
  5. 6. first recorded attempt of immunization, which involved drying and grinding up smallpox scabs, occurred here.
  6. 7. method in which dried pus from smallpox is used to deliberately inoculate a healthy person. originated in Far East in 10th cent. Brought to England in 1721.
  7. 9. cell type which modulates the immune response. recognizes antigen presentation via both MHC I and MHC II.
  8. 11. synonymous with antibody receptor. Y-shaped.
  9. 12. response type involving B cells and antibodies.
  10. 13. T cells cannot partake in an immune response unless antigen ___ occurs via an MHC molecule.
  11. 16. in whole organism vaccines where cells are killed or a virus is deactivated, this quality is retained.
  12. 20. these are used to combat pathogens for a limited time in passive immunity.
  13. 23. there is no memory ___ in passive immunity.
  14. 25. initial exposure to components of a vaccine induce this response.
  15. 27. T cells mature here.
  16. 30. the memory response induced by vaccination is ___, powerful, and sustained.
  17. 31. live ___ cells or viruses can be used in whole organism vaccines.
  18. 34. adaptive immunity involves this, whereas innate immunity does not.
  19. 35. antigenic ___ vaccines are an alternative to whole organism vaccines.
  20. 38. substances which can elicit a response from either B or T cells.
  21. 40. if T cells are stimulated by B cell activity, the activation of B cells is considered this.