Across
- 1. ___ is a biosynthetic precursor of nucleotides
- 4. Allosterically activates PFK1 and *competitively* inhibits FBPase-1
- 8. Converts two 5C sugars to a 3C and 7C sugar, also 4C and 5C sugars to 3C and 6C
- 11. FBPase-2 promotes production of this molecule, stimulating gluconeogenesis
- 13. Main products are NADPH and ribose 5-phosphate
- 16. ATP is a substrate and a negative effector of this enzyme
- 17. G6P dehydrogenase, lactonase, and 6-Phosphogluconate dehydrogenase are enzymes in this phase of the PPP
- 19. Reactions ___ from equilibrium are common points of regulation
- 22. Converts a 3C and 7C sugar to 6C and 4C sugars
- 24. Pyruvate to this molecule to anaerobically regenerate NAD+
- 25. Different enzymes that catalyze the same reaction
Down
- 2. Dephosphorylation is catalyzed by ____
- 3. "Reverse" process of glycolysis that occurs in the liver
- 5. This many nucleoside triphosphates are required to convert pyruvate back to PEP
- 6. Insulin ___ PFK2 to activate it
- 7. Allosterically activates PFK1 and inhibits FBPase-1
- 9. This enzyme promotes production of F26BP, stimulating glycolysis
- 10. Liver enzyme not inhibited by glucose-6-phosphate, so can function at a higher [glucose]
- 12. Allosterically activated by F-1,6-BP and inhibited by ATP, acetyl-CoA, and alanine
- 14. Synthesis of pyruvate and bicarbonate by pyruvate carboxylase to this molecule
- 15. CO2 carrier crucial to synthesis of oxaloacetate
- 18. Anaerobic process of converting glucose to pyruvate
- 20. Glucagon ___ FBPase-2 to activate it
- 21. Phosphorylation is catalyzed by ___
- 23. ___ is an electron donor in the PPP