Biochemical Russian Roulette: Which Cell Survives ?

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Across
  1. 2. central metabolic molecule that enters the Krebs cycle to produce ATP.
  2. 4. organelles where oxidative metabolism and the Krebs cycle occur.
  3. 6. versatile liver cell capable of using multiple fuels and producing ketone bodies.
  4. 7. cytoplasmic pathway that converts glucose to pyruvate and yields small amounts of ATP.
  5. 8. high-energy cell that depends almost entirely on glucose oxidation for ATP.
  6. 10. Krebs cycle enzyme inhibited by fluorocitrate.
  7. 14. process of energy release through electron loss in metabolic pathways.
  8. 17. alternative energy molecules produced by the liver during fasting or PDH deficiency.
  9. 19. mitochondrial pathway where Acetyl-CoA is oxidized to generate energy.
  10. 20. another name for the Krebs cycle.
Down
  1. 1. condition resulting from accumulation of lactate when pyruvate cannot enter the Krebs cycle.
  2. 3. toxic compound that blocks aconitase in the Krebs cycle.
  3. 5. mechanism where a molecule blocks or slows down an enzyme’s function.
  4. 9. sum of all biochemical reactions in a living organism.
  5. 11. main energy currency of the cell.
  6. 12. poison that inhibits the Krebs cycle by forming fluorocitrate.
  7. 13. enzyme that converts pyruvate into Acetyl-CoA.
  8. 15. process by which hepatocytes produce ketone bodies.
  9. 16. ability of cells like hepatocytes to switch between fuel sources.
  10. 18. product of glycolysis that must be converted to Acetyl-CoA to enter the Krebs cycle.