*BIOTECH BRAIN-BOXES*

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Across
  1. 1. Discovered X-rays as a mutagen
  2. 3. Coined the terms 'gene', 'genotype' and 'phenotype'.
  3. 6. 'Host' used in the construction of the first artificial recombinant DNA molecule.
  4. 7. Renamed 'nuclein' as 'nucleic acid' due to its acidic properties.
  5. 10. First restriction endonuclease used.
  6. 11. Father of Eugenics- Genetic improvement of the human race.
  7. 13. Discovered Purins and Pyrimidines bases in nucleic acids.
  8. 14. Bt toxin is produced by this bacterium.
  9. 16. Indian scientist- Developed the chemical method to synthesize RNA
  10. 19. A gene encoding proteins that control cotton bollworms
Down
  1. 2. Discovered A, B, O blood group.
  2. 4. transformation principle
  3. 5. Possess ability to replicate within bacterial cells independent of the control of chromosomal DNA.
  4. 8. Father of experimental genetics
  5. 9. Another term for 'Gene Gun'-used in plant cells.
  6. 12. First to report chromatin.
  7. 15. A bacterium from which a thermostable DNA polymerase is isolated for PCR.
  8. 17. A collection of methods that allows correction of a gene defect that has been diagnosed in a child/embryo.
  9. 18. Adenosine deaminase