BIY 211_quiz 2b

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Across
  1. 3. looping What is done to DNA to bring faraway REs near each other for better crosstalk
  2. 5. Type of transrepression when monomeric NR represses transcription of TFs by interacting with them
  3. 6. Phosphorylation of NR right after synthesis in cells
  4. 7. Coactivator recruited after ligand binding to NR
  5. 9. Type of hormonal action seen in enucleated cells
  6. 12. LBD without any ligand bound
  7. 14. NLS present in this domain of NRs
  8. 15. Transcription of this Clock binding protein is aided by ROR but not Rev-Erb
  9. 17. Type of chromatin when HAT acts on histone
  10. 18. Steroid hormone precursor whose transcription is shut off by glucocorticoid binding to GR
  11. 19. Mammalian ortholog of SWI/SNF proteins with ATPase activity
Down
  1. 1. clamp E542 and K362 form this on either side of LXXLL
  2. 2. Type of TF that remodels chromatin initially to expose Res for other TFs
  3. 4. Conversion of T4 to T3
  4. 7. Receptor _____: What you see when transcriptional activity of multiple HREs > sum of individual HREs
  5. 8. Peptide helix from coactivator binding to NR’s E region
  6. 10. Protein sequestering NF-kappaB in cytoplasm
  7. 11. Type of T helper cells which play important roles in immunity in which RORgammaT is activated
  8. 13. Second zinc finger in DBD, role in dimerization
  9. 16. Helix 12 a.k.a TAD2