Across
- 5. Our Cesium irradiator will need to be replaced with this type someday
- 6. A general term for a testing (or evaluating) one person’s serum/plasma against another person’s red blood cells to check and see if there is an incompatibility (primarily in the ABO and Rh systems).
- 9. the antibody-coated red cells used as a quality control measure for negative indirect or direct antiglobulin tests performed in test tubes
- 10. The lack of A, B, or H antigens on red blood cells and in secretions and plasma.
- 11. refers to transfusion of blood from a different person.
- 14. Modification to a blood product in which cellular blood products are exposed to a specified amount of either gamma rays, x-rays, or ultraviolet B rays (outside of the U.S.).
- 16. to determine whether a pregnant woman has a significant level of antibody that may cause HDN.
- 18. Defined loosely as the rapid administration of a volume of red blood cells roughly equivalent to a “normal” person’s RBC volume.
- 21. A medication recently approved in the U.S. for multiple myeloma treatment
- 22. is a “thiol reagent” that dissolves disulfide bonds between cysteine amino acids, potentially affecting both red cell antigens and antibodies.
- 24. is used when a previously acceptable product becomes questionable due to a variety of factors.
- 25. a test used to demonstrate the presence or absence of unexpected (non-ABO) antibodies.
- 28. Transfusion-related Acute Lung Injury
- 29. An antibody that targets antigens present on the patient or donors’ own red blood cells.
- 30. The process in which free red blood cells are bound together by an antibody and reduced to a visible pellet when centrifuged, most typically in test tubes.
Down
- 1. This type of transfusion is sometimes used for patients with Sickle Cell Anemia or babies with HDN
- 2. A general term for the destruction of red blood cells (RBCs).
- 3. a deposition of indirect bilirubin pigment in basal brain structures (hippocampus, globus pallidus, and other structures), associated with severe hemolytic disease of the fetus/newborn (classically due to HDFN caused by anti-D) or any other clinical situation resulting in severe indirect hyperbilirubinemia.
- 4. Tranfusion-associated circulatory overload
- 7. This type of testing is helpful to determine if a patient has a variant antigen
- 8. A somewhat crude laboratory test used to screen maternal blood samples for the presence of fetal red blood cells.
- 10. refers to a section of a hospital laboratory responsible for the storage and issue of blood products.
- 12. An antibody that reacts against all reagent cells in an antibody panel, rather than against one or more specific cells.
- 13. Acronym for “Low Ionic Strength Saline.”
- 15. refers to evaluation to make as sure as possible that a particular process will perform as expected.
- 17. UMass recently started to perform this type of transfusion to help pregnant patients who are alloimunized
- 19. Serologic test to detect red blood cells (RBCs) that are coated with complement and/or antibodies in-vivo (in the body).
- 20. This test is done to detect antibody and/or complement coating red cells following incubation with serum or plasma in the laboratory.
- 23. transfusion in which the donor and recipient are the same person.
- 26. Removing (or “dissociating”) an antibody that is attached to the surface of a red blood cell.
- 27. A protein or glycoprotein found on the surface of a red blood cell and defined by recognition by a specific alloantibody.