Across
- 1. Drilled pits in bone surface from Collagenase and other enzymes
- 3. Progenitor cell for Osteoclasts that when stimulated by a particular signalling molecule to form a multinucleated cell
- 7. Forms new bones and add growth to existing bone tissue.
- 9. Mature Bone Cells (Trapped in the bone matrix within lacunae, will be eaten by Osteoclasts when they break down bone)
- 10. Released in response to low blood Ca+2 levels, this hormone will increase the release of RANKL and as such Osteoclast action
- 11. Acts as a protective factor against excessive bone remodelling.
Down
- 1. Broken down by HCL and releases Ca+2 into blood stream
- 2. Fate of Osteoclasts (typically) once their work is completed
- 4. Special cells that secretes HCL, and Collagenase to break down bone
- 5. Allows / encourages the absorption of Ca+2 by the intestines. Typically received from sun exposure
- 6. Released by Osteoblast cells once they detect microfractures in the bone structure (Weight) that induces the maturation of Osteoclasts
- 8. Released by Osteoclast cell and binds to RANKL. This slows the activation of Osteoclast