BRAD 2025

2. Samples undergoing this process are usually preserved with a fixative and sliced extremely thin so that the microscopic structures of tissues and cells can be examined.
4. A thin, flexible tube that may be inserted into a blood vessel, body cavity, or hollow organ for easy access.
6. These proteins bind to specific targets within the body. This class of drugs will have a name that ends in -mab.
10. The liquid portion of blood that remains after blood cells and clotting factors have been removed.
11. The study of biochemical and physiological effects that a drug has on the body.
13. This highly contagious viral disease affecting livestock is the only other disease besides smallpox to successfully be eradicated worldwide through human effort and vaccination.
14. Breakthrough drug prescribed for type 2 diabetes and obesity. The non-proprietary name of Ozempic/Wegovy/Rybelsus.
17. This guiding principle in biomedical research aims to improve animal welfare, consisting on reduction, refinement, and replacement.
19. What a new drug must attain before it can be sold for human use.
20. The soft, spongy tissue found inside bones that is responsible for the production of many types of blood cells.
21. The most commonly used laboratory rat strain.

1. These aquatic animals are excellent models in the field of regenerative medicine due to their ability to regenerate their limbs, organs, and parts of the central nervous system.
3. This term refers to a genetically modified mouse in which an existing gene has been inactivated.
5. Though their anatomy and physiology is the most translatable to humans, only about 0.5% of biomedical research uses these animal models.
7. A federally mandated group that oversees all aspects of an institution's animal care and use program.
8. A rodent's total blood volume can be estimated as ___ percent of their bodyweight in grams.
9. A behavior exhibited by rodents that involved searching for and consuming food. Providing opportunities for this behavior is a good form of animal enrichment.
12. The main organ responsible for most drug metabolism.
15. Unlike intravenous which has immediate absorption, ______ dosing routes such as PO, SC, and IP, need time to absorb into the bloodstream.
16. For procedures that involve more than momentary pain or distress, animals are rendered temporarily unconscious using this anesthetic agent.
18. A ventilated enclosure in which gases and vapors are captured and removed from the work area.