C2.1 - Crossword Labs

5. The narrow gap between two neurons where chemical signaling occurs.
8. The process of converting an extracellular signal into a specific intracellular response.
13. Signalling involving the release of hormones into the bloodstream for long-distance communication.
14. A chemical messenger that crosses a synapse to transmit a signal between neurons.
17. The brain region that links the nervous system to the endocrine system.
18. Ligands like steroid hormones that can pass through the bilayer to internal receptors.
19. A hormone that signals the liver to release glucose into the blood.
20. A chemical messenger transported by the blood to act on distant target cells.

1. A mechanism that amplifies a change, moving a system further from its equilibrium.
2. A hormone produced by the pancreas to signal cells to take up glucose.
3. A hormone that maintains the uterine lining during pregnancy or the menstrual cycle.
4. A control mechanism that reverses a change to maintain homeostasis.
6. A general term for a signaling molecule that binds to a specific receptor.
7. Small signaling proteins used extensively in communication between immune cells.
9. An organ that secretes chemical substances such as hormones.
10. Ligands that cannot cross the membrane and must bind to surface receptors.
11. The minimum level of stimulus required to trigger a response in a cell.
12. The primary female sex hormone required for the thickening of the uterine lining.
15. A protein that changes shape upon binding a ligand to initiate a response.
16. A cell that possesses the specific receptor required to respond to a signal.